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  • OAS2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16965
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱(chēng): OAS2抗原(重組蛋白)

英文名稱(chēng): OAS2 Antigen (Recombinant Protein)

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概述

Fusion protein corresponding to a region derived from 11-335 amino acids of human OAS2

技術(shù)規(guī)格

Full name:

2'-5'-oligoadenylate synthetase 2, 69/71kDa

Swissprot:

P29728

Gene Accession:

BC049215

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.