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  • HSD17B12抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17432
    • 應用 : 僅供科研使用
    • 貨期 : 現貨
    • 規(guī)格 :1mg/100ug
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中文名稱:  HSD17B12抗原(重組蛋白)

英文名稱: HSD17B12 Antigen (Recombinant Protein)

別      名: KAR; SDR12C1

儲      存: 冷凍(-20℃)

相關類別 抗原

概  述:

Fusion protein corresponding to a region derived from 25-180 amino acids of human HSD17B12


技術規(guī)格

Full name:

hydroxysteroid (17-beta) dehydrogenase 12

Synonyms:

KAR; SDR12C1

Swissprot:

Q53GQ0

Gene Accession:

BC012043

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.